Department of Biomedical Engineering

Scientists Create a 'Golden Ear' Mouse with Great Hearing as It Ages

What do you get when you cross a mouse with poor hearing and a mouse with even worse hearing? Ironically, a new strain of mice with golden ears - mice that have outstanding hearing as they age.

The work by one of the world's foremost groups in age-related hearing loss, or presbycusis, marks the first time that scientists have created the mouse equivalent of a person withgolden ears - people who are able to retain great hearing even as they grow older. The research at the University of Rochester Medical Center was published online recently in the journal Neurobiology of Aging.

The new mouse is expected to offer clues about how these lucky folks are able to retain outstanding hearing even through old age. Researchers estimate that approximately 5 percent of people, mainly women, fall into this category. The new mice created in the laboratory of Robert Frisina, Ph.D., embody many of the same traits of human golden ears because of an astute cross of two types of mice long popular with researchers.