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2009 Orthopaedic Research Society Annual Meeting

The UR Biomedical Engineering Program was well represented at this year's Annual Meeting of the Orthopaedic Research Society in Las Vegas, Nevada. In addition to several podium and poster presentations by current members of the BME department, it was great to connect with many alumni of the program, who have gone on to graduate degrees, positions in industry, or post-doctoral fellowships. Below is a list of some of the presentations made by our alumni, students and faculty. This list shows the extent and variety of impacts that the UR BME family is making on the field of orthopaedic science.

Presentations by alumni of the program:

  • Bone's Elastic and Viscoelastic Nanomechanical Properties are Modulated by Intensity of Dynamic Ultrasound Mechanical Signals in an Osteopenia Rat Model Suzanne Ferreri, Bing Hu, Roger Talish, Titi Trandafir, Yi-Xian Qin
  • The Effect of Ultrasound Pulse Duration on Bone's Nano-scale Tissue Adaptation in an OVX Osteopenia Model - Elastic and Viscoelastic Nanomechanical Evaluation Suzanne Ferreri, Bing Hu, Yi-Xian Qin

* Suzanne Ferreri (2001) is a Ph.D. candidate at SUNY Stony Brook

  • Prediction of Spatial Patterns of Physical Stimuli Resulting from Mechanical Loading of Tissue Engineered Cartilage using Finite Element Analysis Omotunde Babalola, Lawrence Bonassar

* Tunde Babalola (2002) is a PhD Candidate at Cornell University

  • The Effects of a Variable Stiffness Interface Layer on Load Transfer and Bone Strains in Hip Resurfacing Jason Long, Donald Bartel

* Jason Long (2003) completed his PhD at Cornell University in 2008, and is now a post-doctoral fellow at the University of Michigan Orthopaedic Research Laboratories

  • Wear Assessment of Retrieved Ceramic Femoral Heads Dan Xia Chen
  • Augmentation of Zone II Flexor Tendon Repair using GDF5 in a Rabbit Model R Frank Henn, Christina Kuo, Pasquale Razzano, Dan Xia Chen, Daniel Grande, Scott Wolfe

* Dan Chen (2005) completed her MS Degree from Cornell University in 2008, and is now a research associate at the Hospital for Special Surgery

  • Structural Parameters of Normal and Osteoporotic Human Trabecular Bone are Affected Differently by MicroCT Image Resolution Hanna Isaksson, Juha Töyräs, Mikko Hakulinen, Antti Aula, Inari Tamminen, Petro Julkunen, Heikki Kröger, Jukka Jurvelin
  • Spectroscopic Characterization of Altered Bone Composition Following Osteoporosis or Renal Osteodystrophy Hanna Isaksson, Mikael Turunen, Lassi Rieppo, Simo Saarakkala, Jarno Rieppo, Heikki Kröger, Jukka S Jurvelin
  • Reproducibility and Agreement of MicroCT and Histomorphometry Depend on the Metabolic Status of Human Trabecular Bone Inari Tamminen, Antti Aula, Hanna Isaksson, Jukka S Jurvelin, Heikki Kröger
  • Tissue Composition and Structure Affect Mechanical Response of Articular Cartilage Differently Under Unconfined Compression and Indentation: A Fractional Factorial Design Study Petro Julkunen, Jukka S Jurvelin, Hanna Isaksson

* Hanna Isaksson, who completed her MS in Rochester through an exchange program with Uppsala University in 2003, completed her Ph.D from Eindhoven University in the Netherlands, and is now in a post-doctoral fellowship in Finland

  • Effects of Hemi-Joint Culture on Biological, Biomechanical, and Biochemical Properties of Articular Cartilage William McCarty, Andrea Pallante, Rebecca Rone, Robert Sah
  • Effects of Temperature and Serum on Storage of Fresh Goat Osteochondral Grafts Andrea Pallante, Won Bae, Albert Chen, David Amiel,William Bugbee, Robert Sah

* Andrea Pallante (2005) is a Ph.D. candidate at University of California San Diego

  • Damage Accumulation in Tendon Measured Using Secondary Harmonic Generation and Fourier Spectral Analysis Jedd Sereysky, David Fung, Jelena Basta-Pljakic, Mitchell Schaffler, Evan Flatow

* Jedd Sereysky (2005) is an MD/Ph.D. candidate at Mt. Sinai Medical School

  • The Anterior Stability Provided by the Glenohumeral Capsule May Be Similar Among Patients During Abduction and Mid-Range External Rotation: Finite Element Analysis Nicholas J Drury, Benjamin J Ellis, Patrick McMahon, Richard Debski, Jeffrey A Weiss

* Nick Drury (2006) completed his MS Degree at the University of Pittsburgh, and is now working for Zimmer Orthopaedics in Warsaw, Indiana

  • A Microstructural Model for the Glenohumeral Capsule: Implications for Surgical Repair Carrie Voycheck, Steve Maas, Jeffrey Weiss, Patrick McMahon, Richard Debski

* Carrie Voycheck (2006) is a Ph.D. candidate at University of Pittsburgh

Presentations by current students and faculty:

  • Obesity and Alignment as Increased Risks for Knee Osteoarthritis: Using Computational Models to Explore Clinical Findings Sarah Lancianese, Amy Lerner
  • Understanding the Knee Adduction Moment in Children Who Are Overweight: Considering Both Axial and Medial Ground Reaction Forces Imoh Ikpot, Sarah Lancianese, Amy Lerner
  • Case Study Predicting Subject Specific Proximal Tibial Trabecular Bone Stresses and Strains in Normal Weight and Obese Subjects Sarah Lancianese, Amy Lerner
  • Investigation of Which Factors Matter Most when Predicting Risk of Trabecular Bone Damage in Obesity Sarah Lancianese, Paul Funkenbusch, Amy Lerner
  • In Vivo Normal Knee Kinematics: Are Ethnicity or Gender Influencing Factors? Filip Leszko, Kristen Hovinga, Adrija Sharma, Mohamed Mahfouz, Amy Lerner, Mathew Anderle, Wesley Underwood, Richard Komistek
  • A Compression Model of Vertebral Degeneration Illicits Bone Marrow Edema Signal on CE-MRI Owen Papuga, Steven Proulx, Edmund Kwok, Zhigang You, Paul Rubery, Paul Dougherty, Matthew Hilton, Hani Awad, Edward Schwarz
  • Chondrogenic Differentiation of Adipose Stem Cells in a Cartilage-derived Porous Scaffold Naichen Cheng, Brad Estes, Hani Awad, Farshid Guilak
  • Interstitial Flow Produces a Superficial Zone-Like Layer in Tissue Engineered Cartilage Tony Chen, Michael Zuscik, Hani Awad
  • Anabolic Effects of TGF-β and Low Oxygen on Bioreactor-Cultivated Tissue Engineered Cartilage Tony Chen, Richard Jeffries, Michael Zuscik, Hani Awad
  • Axin2 Controls Bone Remodeling through β-Catenin-BMP Signaling Pathway in Adult Mice Wei Hou, Ying Yan, Dezhi Tang, Jian Huang, Jennifer Jonason,Wei Hsu, Hani Awad, Edward Puzas, Regis O'Keefe, Brendan Boyce, Di Chen
  • Wear debris-induced osteolysis is mediated by PGE2 inductions of RANKL through the EP4 receptor on fibroblasts/osteoblasts Ryosuke Tsutsumi, Chao Xie, Xaochao Wei, Xinping Zhang, Lisa Flick, Edward Schwarz, Regis O'Keefe
  • TAK1 Promotes Chondrocyte Maturation and Joint Development Lea Gunnell, Edward Schwarz, Matthew Hilton, Regis O'Keefe
  • EP1-/- Mice Exhibit Accelerated Fracture Healing Minjie Zhang, HsinChiu Ho, Tzong Sheu, Michael Zuscik, Edward Schwarz, Regis O'Keefe
  • In Vivo Bone Tissue Regeneration Using rAAV-BMP2-Coated Allografts Dan Gazit, Ayelet Ben-Arav, Gadi Pelled, Yoram Zilberman, Colleen Hock, David Reynolds, Edward Schwarz
  • The Involvement of SDF-1/CXCR4 Axis in Endochondral Bone Repair Toshiyuki Kitaori, Hiromu Ito, Edward Schwarz, Takashi Nakamura
  • P38-ATF2 Signaling Regulates Chondrocyte Maturation: the potential novel therapeutics for osteoarthritis Tianfang Li, Lin Gao, Michael Zuscik, Di Chen, Edwards Schwarz, Regis O'Keefe
  • A Rabbit Model of Meniscal Injury and Healing Using Dgemric Imaging to Assess Repair Matthew Wolenski, Abbie Turner, David Reynolds, Edmund Kwok, Zhigang You, Cristin Ferguson, Julia Hwang, Michael Maloney, Edward Schwarz
  • The Histone Deacetylase Inhibitor Vorinostat Sensitizes Human Fibrosarcoma Cells to Chemotherapy Erik Sampson, Edward Schwarz, Regis O'keefe, Randy Rosier
  • The Role of Angiogenic Factors in the Initiation of Renal Cell Carcinoma Metastases to Bone Chao Xie, Dan Li, Colleen Hock, Regis O'Keefe, Edward Schwarz, Susan Bukata
  • The Effects of Chronic Cyclic and Static Loading on the Rabbit Lumbar Spine: An In Vivo Pilot Study Glenn Sanders, Sarah Linley, Daniel Ramsey, Rosalyn Abbott, Edward Puzas, Joseph Glennon, Darryl DiRisio, Clifford Belden, Eric Ledet
  • In Vitro Stimulation of Oxygen Consumption by Lead May Elucidate the Role of Reactive Oxygen Species in Osteoarthritis Jonathan Holz, Tzong Sheu, Roman Eliseve, Thomas Gunter, Michael Zuscik, Edward Puzas