BME Seminar Series: Luiz Meirelles, Asst. Prof. Dentistry and Biomed Eng, UR
Controlling the Bone-Implant Interface
Our goal is to develop implant surface modifications to improve early bone healing and maintain bone support during function. Chemical and topographical modifications added on the implant surface are an excellent alternative to modulate bone formation. Using pre-clinical animal models we are able to screen and develop optimal surface modifications. Histological analyses and biomechanical tests of the intact bone-implant interface can be used to understand the in vivo response and provide guidelines for the continuous development of implant surfaces. The animal models, the surface modifications, the methods to analyze the modified surface, and current results from our Lab will be presented.