BME Seminar Series: Saugata Sinha
Ex-vivo Multispectral Photoacoustic Imaging for the Management of Prostate and Thyroid Cancer
Multispectral Photoacoustic imaging is a rapidly emerging non-invasive soft tissue imaging modality which has the potential to detect tissue abnormality at an early stage. It has the ability to provide important physiological information related to function and molecular composition of the tissue. Photoacoustic images map the spatially varying optical absorption property of tissue. In Multispectral photoacoustic imaging, the soft tissue is imaged with different wavelengths, tuned to the absorption peaks of the different light absorbing tissue constituents or chromophores to obtain images with different contrasts of the same tissue sample. We have developed an acoustic lens based ex-vivo multispectral photoacoustic imaging system. Preliminary results of our ex-vivo human prostate and thyroid studies suggest that, for both prostate and thyroid, multispectral photoacoustic imaging can differentiate among malignant, benign and normal tissue.