Graduate Programs

Graduate Courses

Please see below for detailed information on the courses offered this year.

Fall
Spring

Check the course schedules/descriptions available via the Registrar's Office for the official schedules for the widest range of terms for which such information is available. However, students can choose classes from a variety of programs including Pharmacology & Physiology, Pathology, Biology, Genetics, Chemical Engineering, Mechanical Engineering, Optics, Electrical Engineering and more. Please reference the Graduate Handbook for more information on the wide variety of courses we offer. 


Below you will find a list of all graduate courses that have been offered.

NOTE: Not all of these courses are offered in any given year.

BME 404 COMPUTATIONAL METHODS APPLIED TO BIOLOGICAL SYSTEMS

The aim of this class is to gain experience solving analytically intractable research problems using computational methods. At the beginning of the course, general numerical analysis topics are reviewed. The rest of the course is oriented toward projects. Examples will be drawn from problems of biological systems.

Last Offered: Fall 2016

BME 411 CELLULAR&MOLECULAR BIO FOUND

Molecular biology, biochemistry, and genetics that are required to understand the biomedical and broader biological issues that affect our lives.

Last Offered: Fall 2017

BME 412 VISCO IN BIO TISSUES

Viscoelastic materials have the capacity to both store and dissipate energy. As a result, properly describing their mechanical behavior lies outside the scope of both solid mechanics and fluid mechanics. This course will develop constitutive relations and strategies for solving boundary value problems in linear viscoelastic materials. In addition, the closely-related biphasic theory for fluid-filled porous solids will be introduced. An emphasis will be placed on applications to cartilage, tendon, ligament, muscle, blood vessels, and other biological tissues. Advanced topics including non-linear viscoelasticity, composite viscoelasticity and physical mechanisms of viscoelasticity will be surveyed.

Last Offered: Spring 2017

BME 418 INTRO TO NEUROENGINEERING

Quantitative studies of neural responses at the cellular, circuit, and systems levels. Analytical and computational modeling of neurons, including nonlinear behavior of neurons and neural circuits. Neural coding of information by single cells or neural populations. Applications of neural networks. Techniques for recording and monitoring neural activity, and applications of neural recording and stimulation to neural prostheses.

Prerequisites: BME 260, strong math/computing skill recommended or permission of instructor
Last Offered: Fall 2017

BME 420 BIOMEDICAL NANOTECH

This course is designed to provide students with detailed knowledge of the principles of nanotechnology and their applications in the biomedical field. Topics of study will include synthesis & assembly of nanoscale structures, lithography, and nanobiomaterials. Students will focus on biomedically-relevant topics such as cancer treatment, bone disorder, diabetes; and learn how nanotechnology is helping diagnose, treat, and understand these medical disorders. Recent innovative research in the biomedical field will be highlighted during discussions of the latest journal articles. At the end of the course, students will have an appreciation of the enormous potential of biomedical nanotechnology, its current, and future applications

Last Offered: Fall 2017

BME 425 HUMAN NEUROPHYS MEASUREMENT

No description

Last Offered: Spring 2017

BME 428 PHYSIOLOGICAL CONTROL SYSTMS

This course introduces students to the theory and practice of control systems engineering. Topics include frequency domain modeling, time domain stability, transient and steady-state error analysis, root locus and frequency response techniques and feedback system design. Emphasis is placed on analyzing physiological control systems, but the concepts and design techniques are applicable and applied to a wide variety of other systems including mechanical and electrical systems.

Prerequisites: permission of instructor
Last Offered: Fall 2017

BME 431 FDA & Intellectual Property: Introduction to FDA Processes and Intellectual Property (IP) Considerations for Medical Products

This interactive course will offer students exposure to intellectual property (IP), patenting processes and regulatory pathways for new medical innovations. Students will learn the terminology, processes and challenges involved in FDA regulations, and the protection and evaluation of intellectual property for medical innovations. Differences between Regulatory Affairs and Regulatory Science will be highlighted with opportunities to work on Regulatory Science in a project setting. An emphasis will be placed on ways that knowledge of prior art and regulatory barriers can optimize concept selection, and early phase project planning to best identify projects suitable for commercialization.

Last Offered: Fall 2017

BME 432 FDA & IP COMMERCIALIZATION: Implementing FDA Requirements and Practical Steps to Commercializing Medical Products

This interactive course focuses on Intellectual Property (IP) commercialization and FDA regulatory pathways for new medical innovations. Emphasis will be placed on the ways that knowledge of IP protection and evaluation, and regulatory barriers can optimize design, testing and commercialization strategies. Building on the basics learned in BME431, students will learn about the processes (and barriers) to bringing a product such as a novel medical device through clinical trials.

Last Offered: Spring 2017

BME 442 Microbiomechanics

This course covers the application of mechanical principles to biotechnology and to understanding life at its smallest scales. Topics will vary with each course offering. Sample topics include force generation by protein polymerization, the mechanisms of bacterial motion, and the separation of biological molecules in porous media.

Prerequisites: permission of instructor
Last Offered: Spring 2017

BME 445 BIOMATERIALS SCIENCE AND ENGINEERING

This course provides a background in biomaterials: basic material properties, specifics on ceramics, polymers and metals used in the body, and special topics related to biomaterials including tissue engineering, biological responses to implanted materials, and drug delivery.

Prerequisites: CHM131, CHM132, PHY121, PHY122, MTH 161, MTH162, Biomechanics and BIO110 OR permission of instructor
Last Offered: Fall 2013

BME 448 CONTROLLED RELEASE SYSTEMS

This course will cover the principles, strategies, and materials used in controlled drug delivery systems.

Last Offered: Fall 2015

BME 451 BIOMEDICAL ULTRASOUND

The physical basis for the use of high-frequency sound in medicine (diagnosis, therapy, and surgery) and biology. Topics include acoustic properties of tissues, sound propagation (both linear and nonlinear) in tissues, interactions of ultrasound with gas bodies (acoustic cavitation and contrast agents), thermal and non-thermal biological effects of ultrasound, ultrasonography, dosimetry, hyperthermia and lithotripsy. Graduate students will have extra assignments.

Last Offered: Spring 2017

BME 452 MEDICAL IMAGING: THEORY & IMPLEMENTATION

Physics and implementation of X-ray, ultrasonic, and MR imaging systems. Special attention is given to the Fourier transform relations and reconstruction algorithms of X-ray and ultrasonic-computed tomography, and MRI.

Prerequisites: ECE 242
Last Offered: Fall 2017

BME 453 ADVANCED BIOMEDICAL ULTRASOUND

This course investigates the imaging techniques applied in state-of-the-art ultrasound imaging and their theoretical bases. Topics include linear acoustic systems, spatial impulse responses, the k-space formulation, methods of acoustic field calculation, dynamic focusing and apodization, scattering, the statistics of acoustic speckle, speckle correlation, compounding techniques, phase aberration correction, velocity estimation, and flow imaging. A strong emphasis is placed on readings of original sources and student assignments and projects based on realistic acoustic simulations.

Prerequisites: BME 451 or permission of the instructor
Last Offered: Fall 2017

BME 455 TRANSLATIONAL BIOMEDICAL OPTICS

This course will focus on the macroscopic biomedical optics techniques(e.g. diffuse optical spectroscopy and tomography, photoacoustic tomography) with high potentials for clinical translation. Students will learn the aspects of instrumentation design, analytic and numerical approaches for optical data analysis, and validation of new technologies in the clinical setting.

Last Offered: Fall 2017

BME 459 APPLIED HUMAN ANATOMY

This course analyzes the structural composition of the human body from cellular to organ levels. The goal is to provide a foundation in human anatomy appropriate for students interested in the bioscience and health care professions (e.g. nursing, physical therapy, medicine, bioengineering). Learning objectives will be achieved through a combination of lecture and hands-on (laboratory) approaches, reinforced by clinical examples and analysis of how biomedical devices interface with anatomical structures. In addition, students will participate in small group discussions of clinical case studies, make group presentations of topic appropriate biomedical devices, and prepare a term paper on the subject of their choice selected from a list of topics generated by the instructor.

Prerequisites: Any introductory biology course.
Last Offered: Spring 2017

BME 460 QUANTITATIVE PHYSIOLOGY

A quantitative, model-oriented approach to physiological systems is presented. Topics include muscle and nerve tissue, the cardiovascular system, the respiratory system, the renal system, and a variety of neural systems

Last Offered: Fall 2017

BME 462 CELL & TISSUE ENGINEERING

This course teaches the principles of modern cell and tissue engineering with a focus on understanding and manipulating the interactions between cells and their environment. After a brief overview of Cell and Tissue Engineering, the course covers 5 areas of the field. These are: 1) Physiology for Tissue Engineering; 2) Bioreactors and biomolecule production; 3) Materials for Tissue Engineering; 4) Cell Cultures and bioreactors and 5) Drug Delivery and Drug Discovery. Within each of these topics the emphasis is on analytical skills and instructors will assume knowledge of chemistry, mass transfer, fluid mechanics, thermodynamics and physiology consistent with the Cell and Tissue Engineering Track in BME. In a term project, graduate students must identify a technological need and present orally and in writing a proposal to meet the need.

Last Offered: Spring 2017

BME 465 CELL ADHESION

This course covers quantitative aspects of receptor mediated cell adhesion: Kinetic descriptions, role of mechanical force. Types of adhesion molecules are reviewed with an emphasis on inflammation.

Last Offered: Spring 2011

BME 466 BIOPROCESS ENGINEERING

This course will explore the bioprocesses involved in producing a biopharmaceutical product (therapeutic proteins, cell therapy products, and vaccines). The course will take a stepwise journey through a typical production process from the perspective of a Bioprocess Engineer, starting with cell culture and moving downstream through purification and final fill. Engineering concepts involved in bioreactor design and control, cell removal/recovery operations, and protein purification will be examined. The course will also provide an introduction to the analytical methods used to test biopharmaceutical products for critical quality attributes The role of the regulatory agencies, like the US Food and Drug Administration, and the regulations that govern the industry will be introduced throughout the course in the context of the bioprocess to which they relate. Graduate students will need to complete a semester-end project in order to receive graduate credit for the course.

Last Offered: Spring 2017

BME 467 MODELS & SIMULATIONS OF BME SYSTEMS

Introduction to analytical modeling and computational simulations of systems. Examples will include cardiovascular, respiratory, muscle, neural and population models. Analytical models for several physiological systems will be studied, and simulations will be written in Matlab.

Prerequisites: BME 230 and 221 or permission of instructor
Last Offered: Fall 2011

BME 470 BIOMEDICAL MICROSCOPY

This course covers the principles and practice of light microscopy as applied to biological and medical questions. Topics include basic light microscopy, epifluorescence, confocal and multiphoton laser-scanning microscopy, and selected methods such as CARS, FRET, FRAP, FCS, etc.

Prerequisites: permission of instructor
Last Offered: Fall 2013

BME 474 BIOMED SENSORS,CIRCUITS&INTR

Course will cover circuits and sensors used to measure physiological systems at an advanced level. Both signal conditioning and sensor characteristics will be addressed. Topics will include measurement of strain, pressure, flow, temperature, biopotentials, data acquisition, and electrical safety. The laboratory will focus on the practical implementation of electronic devices for biomedical measurements.

Prerequisites: permission of instructor
Last Offered: Spring 2017

BME 483 BIOSOLID MECHANICS

Application of engineering mechanics to biological tissues including bone, soft tissue, cell membranes, and muscle. Realistic modeling of biological structures, including the heart, cells, and musculoskeletal tissues. Experimental methods and material models.

Last Offered: Fall 2017

BME 485 CELL & MEMBRANE MECHANICS

This course focuses on the fundamental science underlying the mechanical behavior of cell membranes and the formation of adhesive contacts between cells and between cells and substrates. Our approach is to explore mathematical descriptions of the physical properties of biomembrane structures as well as the physics and chemical basis of cell adhesion. Basic aspects of the structure and composition of cell membranes and the classes of adhesion molecules found on cells are reviewed as a basis for the mathematical treatments.

Prerequisites: Some background in mechanics and cell biology recommended.

BME 486 FINITE ELEMENTS

This course provides a thorough grounding on the theory and application of linear finite element analysis in solid and structural mechanics and related disciplines. Topics: matrix structural analysis concepts and computational procedures, review of linear elasticity, variational methods and energy formulation, weighted residual methods and Galerkin techniques, shape functions based on assumed displacements, isoparametric formulation, FE solution of heat transfer problems, global analysis aspects, error estimation and convergence. MATLAB is used extensively througout the course

Prerequisites: ME 226 Finite elements and programming capability in FORTRAN, C, or C++. MATLAB
Last Offered: Fall 2017

BME 487 NONLINEAR FINITE ELEMENT

The theory and application of nonlinear FE methods in solid and structural mechanics, and biomechanics. Topics: review and generalization of linear FE concepts, review of solid mechanics, nonlinear incremental analysis, FE formulations for large displacements and large strains, nonlinear constitutive relations, incompressibility and contact conditions, hyperelastic materials, damage plasticity formulation, solution methods, explicit dynamic formulation.

Last Offered: Spring 2015

BME 489 BIOSENSORS

This course introduces students to the highly interdisciplinary field of biosensors, with focus on electrochemical transduction. After an overview of the fundamental principles, the course will introduce various strategies to apply the scientific theory and mechanisms to practical issues such as immunoassays, detection of DNA mutation or environmental toxins, metabolic activity, and in-vivo neuronal signal monitoring. The students will be exposed to recent publications that highlight key advances in this field and learn how various chemical, biological and engineering concepts are used in synergy to achieve state-of-the-art sensing of important biological molecules. Emphasis is placed on active participation by students, including literature presentations, critical evaluation of articles, concise technical writing and in-depth discussions.

Last Offered: Spring 2017

BME 491 MASTER'S READING IN BME

No description

Last Offered: Fall 2017

BME 492 SP TOP:MEDICAL DEVICE DESIGN

No description

Last Offered: Fall 2016

BME 493 MASTER'S ESSAY

No description

Last Offered: Fall 2017

BME 494 MASTERS INTERNSHIP

No description

Last Offered: Spring 2017

BME 495 MASTER'S RESEARCH IN BME

No description

Last Offered: Fall 2017

BME 496 CURRENT RESEARCH SEMINARS

No description

Last Offered: Fall 2017

BME 502 ANALYTIC FOUNDATIONS IN BME

The goal of this course is to introduce students to a select range of key concepts and methods from engineering and applied mathematics that are common across most subdisciplines of BME and to illustrate by example how these concepts and methods can be applied directly in the study of biological systems and/or for the solving of biological problems. We expect that students completing the course will have acquired basic practical skills to develop novel analytic approaches to biological problems and will be well prepared for subsequent coursework in their chosen discipline.

Last Offered: Fall 2016

BME 504 BME GRADUATE SEMINAR II

No description

Last Offered: Spring 2010

BME 511 CELL & MOLECULAR FOUNDATIONS

Cellular and molecular biology principles geared toward graduate students without detailed background in biological sciences.

Last Offered: Fall 2011

BME 513 INTRODUCTION TO fMRI: IMAGING, COMPUTATIONAL ANALYSIS AND NEURAL REPRESENTATIONS

The core focus of the course will be on how fMRI can be used to ask questions about neural representations and cognitive and perceptual information processing. Some of the questions that the course will address include: 1) The basic fMRI signal just shows activation in different parts of the brain. How can we get from that to addressing questions about neural representations and neural information processing? 2) Ways of relating neural activation to behavioural performance. Can fMRI provide information over and above what can be obtained from behaviour alone? 3) Standard fMRI analysis using the General Linear Model, including preprocessing steps. 4) Multivariate fMRI analysis using machine learning approaches. There will also be a component, about 20% of the class, on the big-picture aspects of MRI physics and physiology which make fMRI possible.

Prerequisites: Graduate-level math course.
Last Offered: Spring 2014

BME 515 ADVANCED TOPICS IN NEURAL CONTROL OF MOVEMENT

This course investigates the neural control of movement beginning with an understanding of muscle properties and mechanisms of contraction. The course continues with an exploration of important conceptual and theoretical issues in the control of movement: the “degrees of freedom” problem and possible solutions, locomotion and central pattern generators, and the roles of cortex and brainstem in motor control.

Prerequisites: NSC 531 or permission of instructor.
Last Offered: Spring 2010

BME 535 SP TOPIC: MED DEVICE DESIGN

No description

Last Offered: Fall 2017

BME 589 WRITING PROPOSALS IN BME

This course covers the essential aspects of organization and content for writing formal scientific proposals. Open to second-year Ph.D. candidates.

Last Offered: Spring 2017

BME 591 PHD READINGS IN BME

No description

Last Offered: Fall 2017

BME 592 SPEC TOPICS: MECHANOBIOLOGY

No description

Last Offered: Fall 2017

BME 593 LABORATORY ROTATIONS IN BME

Attend seminars first half of the semester and then students rotate in at least 3 different labs during the first year of graduate study to learn of the diversity of research opportunities for Ph.D. research.

Last Offered: Spring 2017

BME 594 INTERNSHIP RESEARCH

No description

Last Offered: Summer 2010

BME 594P INTERNSHP RESEARCH PART-TIME

No description

Last Offered: Fall 2017

BME 595 PHD RESEARCH

No description

Last Offered: Fall 2017

BME 595A PHD RESEARCH IN ABSENTIA

No description

Last Offered: Fall 2017

BME 890 SUMMER IN RESIDENCE - MA

No description

Last Offered: Summer 2016

BME 895 CONT OF MASTER'S ENROLLMENT

No description

Last Offered: Fall 2017

BME 897 MASTER'S DISSERTATION

No description

Last Offered: Fall 2017

BME 897A MASTERS IN-ABSENTIA

No description

Last Offered: Fall 2017

BME 899 MASTER'S DISSERTATION

No description

Last Offered: Fall 2017

BME 985 LEAVE OF ABSENCE

No description

Last Offered: Fall 2017

BME 986V FULL TIME VISITING STUDENT

No description

Last Offered: Fall 2017

BME 990 SUMMER IN RESIDENCE

No description

Last Offered: Summer 2015

BME 995 CONT OF DOCTORAL ENROLLMENT

No description

Last Offered: Fall 2017

BME 997 DOCTORAL DISSERTATION

No description

Last Offered: Fall 2017

BME 997A DOCT DISSERTATN IN ABSENTIA

No description

Last Offered: Spring 2017

BME 999 DOCTORAL DISSERTATION

No description

Last Offered: Fall 2017

BME 999A DOCT DISSERTATN IN ABSENTIA

No description

Last Offered: Spring 2017

BME 999B PHD IN-ABSENTIA ABROAD

No description

Last Offered: Fall 2017